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Обменяемся опытом !? / Советы бывалых / Serevent Preis
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: 29 Октябрь 2015, 16:45:27
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The active component of SEREVENT DISKUS is salmeterol xinafoate, a beta2- adrenergic bronchodilator. Salmeterol xinafoate is the racemic form of the 1-hydroxy-2- naphthoic acid salt of salmeterol. It has the chemical name 4-hydroxy-a1-[[[6-(4- phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol, 1-hydroxy-2- naphthalenecarboxylate and the following chemical structure: SEREVENT DISKUS (salmeterol xinafoate inhalation powder) Structural Formula Illustration Salmeterol xinafoate is a white powder with a molecular weight of 603.8, and the empirical formula is C25H37NO4•C11H8O3. It is freely soluble in methanol; slightly soluble in ethanol, chloroform, and isopropanol; and sparingly soluble in water. SEREVENT DISKUS is a teal green plastic inhaler containing a foil blister strip. Each blister on the strip contains a white powder mix of micronized salmeterol xinafoate salt (72.5 mcg, equivalent to 50 mcg of salmeterol base) in 12.5 mg of formulation containing lactose monohydrate (which contains milk proteins). After the inhaler is activated, the powder is dispersed into the airstream created by the patient inhaling through the mouthpiece. Under standardized in vitro test conditions, SEREVENT DISKUS delivers 47 mcg of salmeterol base per blister when tested at a flow rate of 60 L/min for 2 seconds. In adult subjects with obstructive lung disease and severely compromised lung function (mean FEV1 20% to 30% of predicted), mean peak inspiratory flow (PIF) through a DISKUS® inhaler was 82.4 L/min (range: 46.1 to 115.3 L/min). The actual amount of drug delivered to the lung will depend on patient factors, such as inspiratory flow profile. What are the possible side effects of salmeterol inhalation (Serevent Diskus)? Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects: chest pain, fast or pounding heartbeats, tremors, shaking, or restless feeling; skin rash, bruising, severe tingling, numbness, pain, muscle weakness; wheezing, choking, or other breathing problems after using this medication; or worsening asthma symptoms. Less serious side effects may... Read All Potential Side Effects and See Pictures of Serevent Preis Diskus » What are the precautions when taking salmeterol xinafoate (Serevent Diskus)? Before using this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this drug, tell your doctor or pharmacist your medical history, especially of: heart problems (e.g., angina, irregular heartbeat), high blood pressure, diabetes, liver problems, seizures, thyroid problems (e.g., overactive thyroid). Salmeterol may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can infrequently result in serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right. Treatment Of Asthma SEREVENT DISKUS is indicated for the treatment of asthma and in the prevention of bronchospasm only as concomitant therapy with a long-term asthma control medication, such as an inhaled corticosteroid, in patients aged 4 years and older with reversible obstructive airway disease, including patients with symptoms of nocturnal asthma. LABA, such as salmeterol, the active ingredient in SEREVENT DISKUS, increase the risk of asthma-related death [see WARNINGS AND PRECAUTIONS]. Use of SEREVENT DISKUS for the treatment of asthma without concomitant use of a long-term asthma control medication, such as an inhaled corticosteroid, is contraindicated [see CONTRAINDICATIONS]. Use SEREVENT DISKUS only as additional therapy for patients with asthma who are currently taking but are inadequately controlled on a long-term asthma control medication, such as an inhaled corticosteroid. Once asthma control is achieved and maintained, assess the patient at regular intervals and step down therapy (e.g., discontinue SEREVENT DISKUS) if possible without loss of asthma control and maintain the patient on a long-term asthma control medication, such as an inhaled corticosteroid. Do not use SEREVENT DISKUS for patients whose asthma is adequately controlled on low- or medium-dose inhaled corticosteroids. Pediatric and Adolescent Patients If adherence cannot be assured, a fixed-dose combination product containing both an inhaled corticosteroid and a LABA is recommended. Important Limitation of Use SEREVENT DISKUS is NOT indicated for the relief of acute bronchospasm. Prevention Of Exercise-Induced Bronchospasm SEREVENT DISKUS is also indicated for prevention of exercise-induced bronchospasm (EIB) in patients aged 4 years and older. Use of SEREVENT DISKUS as a single agent for the prevention of EIB may be clinically indicated in patients who do not have persistent asthma. SEREVENT DISKUS is indicated for the long-term twice-daily administration in the maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD) (including emphysema and chronic bronchitis).
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Обменяемся опытом !? / Советы бывалых / Flonase Preis
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: 22 Октябрь 2015, 17:10:37
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Flonase is on tap as a generic drug, and dosing is usually administered as two sprays in each nostril once every day, or at one aerosol in each nostril twice daily. The most clich‚d side effects of Flonase (fluticasone) take in: migraine, back toil, prickly throat, sneezing, cough, nausea, vomiting, menstrual problems, loss of benefit in relations, and nosebleeds. Stimulant interactions and warnings comprise Norvir (ritonavir) and Nizoral (ketoconazole). If your doctor has directed you to work this medication, about that he or she has judged that the better to you is greater than the chance of side effects. Multitudinous people using this medication do not have pensive side effects. Tattle your doctor right away if you have on the agenda c trick any significant side effects, including: affection pain, facial woe, signs of nasal check compensation (such as affliction, severe nosebleeds, a tireless whistling ring from your nose), white patches in your nose/back of your throat, pain when swallowing, persistent sore throat. Hardly ever, it is imaginable that corticosteroids specified in the nose devise be engaged into the bloodstream. This can lead to side effects of too much corticosteroid. These side effects are more credible in children and people who use this medication on a eat one's heart out on the dot and in high doses. Word your doctor goodness away if any of the following side effects occur: unusual/extreme tiredness, weight trouncing debits, problem, nodule ankles/feet, increased thirst/urination, envisaging problems. A very serious allergic effect to this drug is rare. However, cause medical alleviate right away if you intimation any symptoms of a serious allergic reprisal, including: rash, itching/swelling (strikingly of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete record of admissible side effects. If you mind other effects not listed above, junction your doctor or pill roller Clinical Trials Episode Because clinical trials are conducted beneath everywhere varying conditions, adverse resistance rates observed in the clinical trials of a benumb cannot be immediately compared with rates in the clinical trials of another tranquillizer and may not mull over the rates observed in practice. In controlled US clinical trials, more than 3,300 subjects with allergic and nonallergic rhinitis received treatment with intranasal fluticasone propionate. In regular, adverse reactions in clinical trials accept been pre-eminently associated with irritation of the nasal mucous membranes, and the adverse reactions were reported with roughly the unchanged frequency by subjects treated with placebo. Less than 2% of subjects in clinical trials discontinued because of adverse reactions; this rate was comparable for agency placebo and active comparators. The safety details described under are based on 7 placebo-controlled clinical trials in subjects with allergic rhinitis. The 7 trials included 536 subjects (57 girls and 108 boys aged 4 to 11 years, 137 female and 234 masculine adolescents and adults) treated with Flonase Deutschland 200 mcg a single time finally daily beyond 2 to 4 weeks and 2 placebo-controlled clinical trials which included 246 subjects (119 female and 127 manly adolescents and adults) treated with FLONASE 200 mcg once daily to 6 months (Pigeon-hole 1). Also included in Table 1 are adverse reactions from 2 trials in which 167 children (45 girls and 122 boys grey 4 to 11 years) were treated with FLONASE 100 mcg once everyday respecting 2 to 4 weeks.Other adverse reactions with FLONASE Nasal Make known observed with an rate less than or level pegging to 3% but greater than or congruous to 1% and more common than with placebo included: blood in nasal mucus, runny nose, abdominal discomfort, diarrhea, fever, flu-like symptoms, aches and pains, dizziness, and bronchitisPostmarketing Sagacity In summation to adverse events reported from clinical trials, the following adverse events obtain been identified during postapproval use of intranasal fluticasone propionate. Because these reactions are reported voluntarily from a citizenry of occasional judge, it is not in perpetuity achievable to reliably feeling their frequency or locate a causal relationship to sedative exposure. These events contain been chosen for the sake of grouping correct to either their seriousness, frequency of reporting, or causal bearing to fluticasone propionate or a coalition of these factors. General Disorders and Administration Plat Conditions Hypersensitivity reactions, including angioedema, coat multitude, edema of the face and whimsically, pruritus, urticaria, bronchospasm, wheezing, dyspnea, and anaphylaxis/anaphylactoid reactions, which in rare instances were severe. Ear and Labyrinth Disorders Every other or deprivation of coherence of taste and/or smell and, rarely, nasal septal perforation, nasal gumboil, awkward throat, throat irritation and dryness, cough, hoarseness, and chance changes.
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Обменяемся опытом !? / Советы бывалых / Astelin kaufen Ohne Rezept
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: 20 Октябрь 2015, 15:32:44
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Seasonal Allergic Rhinitis The recommended dosage of Astelin Nasal Out in adults and pubescent patients 12 years and older with vasomotor rhinitis is two sprays per nostril twice daily. Distinguished Supervision Instructions When Astelin Nasal Butter has not been utilized by reason of 3 or more days, reprime with 2 sprays or until a elegant mist appears. Astelin (azelastine hydrochloride) Nasal Duvet, 137 micrograms (mcg), is an antihistamine formulated as a metered-spray solution for intranasal administration. Azelastine hydrochloride occurs as a silver, wellnigh odorless, crystalline powder with a unappetizing taste. It has a molecular weight of 418.37. It is sparingly soluble in water, methanol, and propylene glycol and reduce soluble in ethanol, octanol, and glycerine. It has a melting station of beside 225°C and the pH of a saturated elucidation is between 5.0 and 5.4. Its chemical fame is (±)-1-(2H)-phthalazinone,4-[(4chlorophenyl) methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-, monohydrochloride. Its molecular pattern is C22H24ClN3O•HCl with the following chemical order: ASTELIN (azelastine hydrochloride) Structural Blueprint Depiction Astelin Nasal Spray contains 0.1% azelastine hydrochloride in an aqueous elucidation at pH 6.8 ± 0.3. It also contains benzalkonium chloride (125 mcg/mL), edetate disodium, hypromellose, citric acid, dibasic sodium phosphate, sodium chloride, and purified water. After priming [see DOSAGE AND ADMINISTRATION], each metered spray delivers a 0.137 mL manner book containing 137 mcg of azelastine hydrochloride (interchangeable to 125 mcg of azelastine wicked). The grit can commit 200 metered sprays.What are the precautions when taking azelastine hydrochloride (Astelin)? In the forefront using azelastine, let slip your doctor or posologist if you are allergic to it; or if you have any other allergies. This artifact may contain still ingredients (such as preservatives like benzalkonium chloride), which can source allergic reactions or other problems. Talk to your pill pusher in behalf of more details. Ahead using this medication, tell your doctor or pharmacist your medical dead letter, particularly of: kidney problems. This drug may establish you drowsy. Do not urge, basis machinery, or do any interest that requires alertness until you are steadfast you can put up such activities safely. Limit inebriating beverages. This medication should be reach-me-down only when clearly needed during pregnancy. Chat about the risks and benefits with your doctor. It is not known whether this... Astelin kaufen Nasal Spray is indicated an eye to the treatment of the symptoms of seasonal allergic rhinitis in adults and pediatric patients 5 years and older, and owing the treatment of the symptoms of vasomotor rhinitis in adults and adolescent patients 12 years and older.What is Astelin? Astelin (azelastine) is an antihistamine that reduces the effects of halfwit chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, pallid eyes, and runny nose. Astelin Nasal Atomizer prevents sneezing, itching, runny nose, and other nasal symptoms of allergies. This nostrum is in compensation seasonal allergies in adults and children who are at least 2 years over the hill, and an eye to year-round allergies in adults and children as green as 6 months old. Astelin may also be tempered to for the benefit of purposes not listed in this medication guide. Leading communication Go along with all directions on your drug dub and package. Report each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Astelin may impair your ratiocinative or reactions. Be careful if you ram or do anything that requires you to be alert. More willingly than using Astelin, reproach your doctor if you regularly press into service other medicines that make you drowsy (such as stereotyped or allergy remedy, sedatives, anaesthetic pain cure-all, sleeping pills, muscle relaxers, and medicine for seizures, sadness, or eagerness). They can add to sleepiness caused at near Astelin. Slideshow: Stopper Interdiction Tips - Seasonal Allergies Garnish Prohibition Tips - Seasonal Allergies Drinking demon rum can expand certain side effects of Astelin. Hearing your doctor if your symptoms do not rectify, or if they go to worse while using Astelin. Stop using this medicine and call your doctor at positively if you fool fast or uneven heartbeats, tightness in your box, or if you feel suddenly of breath.Before charming this medicine You should not use Astelin if you are allergic to azelastine. To skedaddle unavoidable Astelin Nasal Spindrift is safe representing you, bring to light your doctor about all of your medical conditions. Confess your doctor if you are breast-feeding a baby.
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Обменяемся опытом !? / Советы бывалых / Zyrtec kaufen Ohne Rezept
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: 19 Октябрь 2015, 18:13:24
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In supplement, worry and nausea occurred in more than 2% of the patients, but were more common in placebo patients. Placebo-controlled trials up to 4 weeks duration included 168 pediatric patients venerable 2 to 5 years who received cetirizine, the majority of whom received individual always doses of 5 mg. The the greater part of adverse reactions reported in pediatric patients elderly 2 to 11 years with ZYRTEC (cetirizine) were mild or moderate. In placebo-controlled trials, the incidence of discontinuations due to adverse reactions in pediatric patients receiving up to 10 mg of ZYRTEC (cetirizine) was uncommon (0.4% on ZYRTEC (cetirizine) vs. 1.0% on placebo). Table 2 lists adverse experiences which were reported for ZYRTEC (cetirizine) 5 and 10 mg in pediatric patients aged 6 to 11 years in placebo-controlled clinical trials in the Collaborative States and were more mean with ZYRTEC (cetirizine) than placebo. Of these, abdominal torment was considered treatment-related and somnolence appeared to be dose-related, 1.3% in placebo, 1.9% at 5 mg and 4.2% at 10 mg. The adverse experiences reported in pediatric patients grey 2 to 5 years in placebo-controlled trials were qualitatively similar in creation and on average equivalent in frequency to those reported in trials with children elderly 6 to 11 years. In the placebo-controlled trials of pediatric patients 6 to 24 months of period, the incidences of adverse experiences were almost identical in the cetirizine and placebo treatment groups in each study. Somnolence occurred with essentially the same frequency in patients who received cetirizine and patients who received placebo. In a study of 1 week duration in children 6-11 months of stage, patients who received cetirizine exhibited greater irritability/fussiness than patients on placebo. In a study of 18 months duration in patients 12 months and older, insomnia occurred more again in patients who received cetirizine compared to patients who received placebo (9.0% v. 5.3%). In those patients who received 5 mg or more per time of cetirizine as compared to patients who received placebo, lassitude (3.6% v. 1.3%) and malaise (3.6% v. 1.8%) occurred more frequently. The following events were observed now (less than 2%), in either 3982 adults and children 12 years and older or in 659 pediatric patients superannuated 6 to 11 years who received ZYRTEC (cetirizine) in U.S. trials, including an open adult chew over of six months duration. A causal relationship of these infrequent events with Zyrtec kaufen (cetirizine) charge has not been established. Autonomic Nervous Scheme: anorexia, flushing, increased salivation, urinary retention. Cardiovascular: cardiac lemon, hypertension, palpitation, tachycardia. Inner and Incidental Needles Systems: deviating coordination, ataxia, jumble, dysphonia, hyperesthesia, hyperkinesia, hypertonia, hypoesthesia, rush cramps, migraine, myelitis, paralysis, paresthesia, ptosis, syncope, tremor, twitching, vertigo, visual grassland defect. Gastrointestinal: abnormal hepatic activity, aggravated tooth caries, constipation, dyspepsia, eructation, flatulence, gastritis, hemorrhoids, increased disposition, melena, rectal hemorrhage, stomatitis including ulcerative stomatitis, vernacular discoloration, tongue edema. Genitourinary: cystitis, dysuria, hematuria, micturition frequency, polyuria, urinary incontinence, urinary essay infection. Hearing and Vestibular: deafness, earache, ototoxicity, tinnitus. Metabolic/Nutritional: dehydration, diabetes mellitus, thirst. Musculoskeletal: arthralgia, arthritis, arthrosis, muscle puniness, myalgia. Psychiatric: abnormal thinking, agitation, amnesia, apprehension, decreased libido, depersonalization, economic decline, excitable lability, euphoria, impaired concentration, insomnia, nervousness, paroniria, nap disorder. Respiratory Modus operandi: bronchitis, dyspnea, hyperventilation, increased sputum, pneumonia, respiratory disorder, rhinitis, sinusitis, upper respiratory plot infection. Reproductive: dysmenorrhea, female chest suffering, intermenstrual bleeding, leukorrhea, menorrhagia, vaginitis. Reticuloendothelial: lymphadenopathy. Overlay: acne, alopecia, angioedema, bullous spouting, dermatitis, tiresome skin, eczema, erythematous rash, furunculosis, hyperkeratosis, hypertrichosis, increased sweating, maculopapular imprudent, photosensitivity reaction, photosensitivity toxic reaction, pruritus, purpura, brash, seborrhea, incrustation disturbance, peel nodule, urticaria. Prime Senses: parosmia, sample detriment, taste perversion. Chimera: blindness, conjunctivitis, taste torture, glaucoma, denial of accommodation, ocular hemorrhage, xerophthalmia. Fuselage as a Whole: accidental wound, asthenia, back pain, casket affliction, enlarged abdomen, guts edema, fever, generalized edema, touchy flashes, increased weight, member edema, malaise, nasal polyp, despair, pallor, periorbital edema, peripheral edema, rigors. Occasional instances of fugacious, reversible hepatic transaminase elevations have occurred during cetirizine therapy. Hepatitis with expressive transaminase elevation and elevated bilirubin in association with the use of ZYRTEC (cetirizine) has been reported. Post-Marketing Affair In the post-marketing duration, the following additional rare, but potentially tyrannical adverse events set up been reported: aggressive response, anaphylaxis, cholestasis, convulsions, glomerulonephritis, hallucinations, hemolytic anemia, hepatitis, orofacial dyskinesia, severe hypotension, stillbirth, suicidal ideation, suicide and thrombocytopenia. SIDE EFFECTS Controlled and uncontrolled clinical trials conducted in the Collaborative States and Canada included more than 6000 patients ancient 12 years and older, with more than 3900 receiving ZYRTEC (cetirizine) at doses of 5 to 20 mg per day. The duration of treatment ranged from 1 week to 6 months, with a surely disclosure of 30 days. Most adverse reactions reported during remedy with ZYRTEC (cetirizine) were mild or moderate. In placebo-controlled trials, the incidence of discontinuations correct to adverse reactions in patients receiving ZYRTEC (cetirizine) 5 or 10 mg was not significantly particular from placebo (2.9% vs. 2.4%, severally). The amount of somnolence associated with ZYRTEC (cetirizine) was dosage coupled, 6% in placebo, 11% at 5 mg and 14% at 10 mg. Table 1 lists adverse experiences in patients aged 12 years and older which were reported after ZYRTEC (cetirizine) 5 and 10 mg in controlled clinical trials in the Shared States and that were more common with ZYRTEC (cetirizine) than placebo.
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